Devil's Claw Capsules | Buy Devil's Claw - Arkopharma 9.5mg 90 capsules

	Good for: Help with reducing pain and inflammation associated with arthritis.
	Things to be aware of: Devil's claw should not be used by people with gastric or duodenal ulcers. People with gallstones should consult a doctor before using devil's claw. p&p from £2.50+VAT no matter how much you buy!

Devil's Claw

435mg, 9.5mg glucoiridoids

Devil's claw is a plant native to southern Africa. Its name comes from the small hooks on the plant's fruit. The active ingredients in devil's claw are believed to be iridoid glycosides called harpagosides, which are found in the secondary root.

The primary use of devil's claw today is for conditions that cause inflammation and pain:

• Back pain
• Neck pain
• Rheumatoid arthritis
• Osteoarthritis
• Tendinitis

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Dosage

One capsule morning, noon and evening during meals with a large glass of water. The dosage may be increased to six capsules per day if necessary.

The recommended daily intake should not be exceeded.

Devil's claw should not be used by people with gastric or duodenal ulcers.

People with gallstones should consult a doctor before using devil's claw.

People with diabetes or who are taking medication that affects their blood sugar should only use devil's claw under the supervision of a qualified health practitioner. In one study, devil's claw extract resulted in reductions in blood glucose in fasted normal and diabetic animals.

Devil's claw should not be used by people who are or may be pregnant, as it is believed to cause uterine contractions.

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Does it work?

There is some evidence for the use of devil's claw, however one larger, randomized controlled trial found only a modest benefit.

A German study examined the use of devil's claw for slight to moderate back, neck, and shoulder muscle tension and pain. In the 4-week study, 31 people took 480 mg twice a day and 32 people took a placebo. The results showed there was a significant reduction in pain in the people taking devil's claw compared to the placebo group.

A study published in the journal Rheumatology compared a devil's claw extract providing 60 mg harpagosides a day and and 12.5 mg a day of the anti-inflammatory Vioxx (now off the market) for 6 weeks in 79 patients with an acute exacerbation of low back pain. Devil's claw was as effective as Vioxx in reducing pain.

A study published in the journal Joint Bone Spine compared six 435 mg capsules of powdered devil's claw extract a day (which provides about 60 mg per day of harpagosides) with 100 mg a day of a European osteoarthritis drug called diacerhein in 122 patients with osteoarthritis of the knee or hip. After four months, devil's claw was as effective as the diacerhein at relieving pain, improving mobility, and reducing the need for back-up medication (such as anti-inflammatory and analgesic drugs). Although this sounds great, the results aren't as impressive in light of a 3-year placebo-controlled study found diacerhein was ineffective at reducing osteoarthritis symptoms.

In a European Journal of Anaesthesiology 4-week study, 197 people with back pain rated at 5/10 or higher on a pain scale received a standardized daily dose of 50 mg or 100 mg harpagosides or placebo. Devil's claw seemed to reduce pain more than placebo.

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